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Accurate continuous drug delivery at low infusion rate with a novel microvolumetric infusion pump (MVIP): pump design, evaluation and comparison to the current standard

机译:使用新型微量输液泵(mVIp)以低输注速率准确连续输送药物:泵设计,评估和与当前标准的比较

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摘要

Infusion devices for continuous and precise drug administration are indispensable tools in anaesthesia and critical care medicine. Problems such as start-up delays, non-continuous flow and susceptibility to hydrostatic pressure changes at low infusion rates resulting in accidental bolus release or prolonged flow interruption are inherent to current infusion technology. In order to improve precise drug delivery, an innovative technical concept has been realised in a novel microvolumetric infusion pump (MVIP) device. The MVIP principle includes repeated filling and emptying of a non-compliant microsyringe without the use of valves. The performance of the MVIP prototype has been evaluated and compared with standard syringe infusion pump assemblies. The novel MVIP concept has thereby proven to eliminate most problems during infusion start-up, steady state flow and vertical pump displacement, and has the potential of revolutionising infusion technology and setting a new dimension in patient safety.
机译:在麻醉和重症监护医学中,用于连续且精确地给药的输液设备是必不可少的工具。当前输液技术固有的问题包括启动延迟,流动不连续以及在低输注速率下对静水压力变化的敏感性,从而导致意外推注释放或长时间的流中断。为了改善精确的药物输送,已经在新颖的微体积输液泵(MVIP)设备中实现了创新的技术概念。 MVIP原理包括不使用阀门重复填充和排空不合格的微注射器。 MVIP原型的性能已得到评估,并与标准的注射器输液泵组件进行了比较。事实证明,新颖的MVIP概念可以消除输液启动过程中的大多数问题,稳态流量和垂直泵排量,并且具有革新输液技术并为患者安全设定新维度的潜力。

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